Tretinoin/Hydroquinone Cream

This compounded cream combines tretinoin, a prescription retinoid that promotes skin cell turnover, with hydroquinone, a skin lightening agent that reduces the production of melanin. The combination is prescribed for hyperpigmentation concerns under the supervision of a licensed prescriber. Healthville Pharmacy prepares this cream in our licensed compounding facility to the concentrations your prescriber orders, which allows the formulation to be individualized to your skin and adjusted over time.

Uses & Benefits

This compounded preparation may be prescribed for hyperpigmentation conditions such as melasma, post-inflammatory hyperpigmentation, and uneven skin tone, as part of a treatment plan supervised by a licensed prescriber. Potential benefits may include: May support a more even skin tone with consistent use as directed. Combines two mechanisms in one preparation: increased cell turnover from tretinoin and reduced melanin production from hydroquinone. Compounded concentrations are individualized to your prescription. Hydroquinone containing preparations are typically prescribed for limited treatment periods with breaks as directed by your prescriber. Results develop gradually and vary by individual, and daily sun protection is essential, since sun exposure works directly against the goals of this treatment.

Dosage, Concentration & Route

Route: Topical application to intact skin only. Form: Compounded cream, 30g. Concentration: Tretinoin 0.25% / Hydroquinone 6.25%, or as individualized by prescription. Apply a thin layer to the affected area as directed by your prescriber, typically in the evening. Avoid the eyes, mouth, and other mucous membranes. Use daily sun protection. Do not use more often or longer than prescribed.

Side Effects

Possible side effects include: Dryness, peeling, or flaking Redness or irritation at the application site Burning or stinging on application Increased sensitivity to sunlight Contact your prescriber if irritation is severe or persistent. With prolonged or excessive use of hydroquinone, a rare darkening of the skin (ochronosis) has been reported. Use only for the duration your prescriber directs, and report any unexpected darkening of the treated area promptly. Seek immediate care for signs of a severe allergic reaction such as difficulty breathing or swelling of the face, lips, or tongue.

Storage

Store at controlled room temperature 68°F to 77°F (20°C to 25°C). Keep the container tightly closed, protected from light and heat. Keep out of reach of children and pets.

Frequently Asked Questions

Do I need a prescription?

Yes. This preparation is dispensed only against a valid prescription from a licensed prescriber.

Why is this compounded?

This specific combination and the individualized concentrations are not commercially manufactured as a single product. A licensed compounding pharmacy like Healthville prepares it for an individual patient against a prescription.

How long will I use it?

Hydroquinone containing preparations are typically prescribed for defined treatment periods rather than indefinite use. Your prescriber sets the duration and any treatment breaks, and it is important to follow that schedule.

How do I order?

Your prescriber sends the prescription to Healthville, we verify and prepare it, and it ships to you with tracking.

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