Low Dose Naltrexone (LDN) Compounded
Naltrexone is an opioid receptor antagonist that has been part of clinical practice for decades. Beyond its traditional uses, prescribers increasingly order naltrexone at customized strengths, including low dose regimens that are not manufactured commercially and can only be prepared by a compounding pharmacy. Healthville Pharmacy prepares compounded naltrexone in our licensed facility to the exact strength and form your prescriber orders, dispensed under pharmacist supervision.
Uses & Benefits
Low Dose Naltrexone (LDN) is a compounded prescription medication that may be prescribed off-label to help regulate immune system activity and reduce inflammation. At low doses, naltrexone temporarily blocks opioid receptors, which is believed to stimulate the body's production of endorphins and enkephalins that help modulate immune function and pain perception. Healthcare providers may prescribe LDN as part of a comprehensive treatment plan for certain chronic inflammatory, autoimmune, and pain-related conditions. Potential Benefits: May help reduce chronic pain Supports healthy immune system regulation May decrease inflammation May improve overall quality of life May help reduce fatigue in some chronic conditions May improve sleep quality for some patients May support management of certain autoimmune disorders Compounded strengths can be customized to individual patient needs Because many uses of LDN are considered off-label, individual results vary, and treatment should be supervised by a qualified healthcare provider.
Dosage, Concentration & Route
Route: Oral capsule; often taken at bedtime per prescriber. Compounded strengths commonly include: 4.5 mg Customized strengths as prescribed Typical Dosage: Many patients begin treatment with a low dose that is gradually increased based on tolerability and clinical response. A commonly prescribed maintenance dose is 4.5 mg taken once daily, although your healthcare provider may recommend a different dosage. Take exactly as prescribed. Do not increase or discontinue your medication without consulting your healthcare provider.
Side Effects
Possible side effects include: Vivid dreams Difficulty sleeping (especially during the first few weeks) Headache Nausea Mild stomach discomfort Fatigue Anxiety Dizziness These effects are generally mild and often improve as treatment continues. Critical: naltrexone blocks opioid medications. Do not use if you take opioids or are opioid dependent, and inform every provider you take it, especially before surgery or pain treatment. Seek immediate medical attention if you experience: Difficulty breathing Swelling of the face, lips, tongue, or throat Severe allergic reaction Persistent severe abdominal pain Notify your healthcare provider if side effects become bothersome or persistent.
Storage
Store at controlled room temperature between 68°F and 77°F (20°C to 25°C). Keep the medication: In its original prescription container Tightly closed Protected from moisture Protected from excessive heat Away from direct sunlight Keep out of reach of children and pets.
Frequently Asked Questions
Do I need a prescription?
Yes. Compounded naltrexone is dispensed only with a valid prescription from a licensed prescriber. If you do not have one, a telehealth evaluation can determine whether treatment is appropriate for you.
Why is this compounded?
Commercially manufactured naltrexone comes in limited fixed strengths. When a prescriber wants a strength or regimen outside those options, a licensed compounding pharmacy like Healthville prepares it for that individual patient.
How do I order?
Your prescriber sends the prescription directly to Healthville Pharmacy. We verify it, prepare your medication, and ship it to you with tracking, with our pharmacists available for questions throughout.
How is it shipped?
In discreet, protective packaging with tracking, handled according to the requirements of your specific preparation.